| Name | Description | Aetiology / Treatment |
| Bone Tumour Neoplasia and Osteosarcoma | Commonly at ends of long bones of forelimbs but also in axial skeleton or elsewhere | Breed at increased risk on basis of cases series |
| Cruciate Ligament Rupture | Rupture of the ligament over the stifle joint | Believed inherited but mode of inheritance unknown. Rest, surgery |
| Elbow Dysplasia | Swollen painful elbows and lameness, usually caused by ununited anconeal or coronoid process | Inherited - Polygenic. Metabolic abnormalities e.g. hormone imbalance |
| Ectropion | Lower eyelid turns outward | Inherited - Surgery |
| Entropion | Eyelids turn inwards causing irritation of the eyeball | Inherited - Surgery but not before 6 months of age owing to changing structure of eye and skull prior to this age |
| Microphthalmia with Multiple Ocular Defects | Microphakia or aphakia, acoria, peripheral anterior synechia & retinal dysplasia | Familial - mode of transmission unknown |
| Ocular Dermoid Cysts | Patch of skin located on the cornea, causing eye irritation | Familial - probably simplex with environmental factors. Relationship to feeding is not clear |
| Epilepsy (Idiopathic) | Fitting> | Believed inherited but mode of inheritance not known. Controlled by drugs (Mysolin) |
| Gastic Dilatation/Volvulus (GDV) Bloat | Distended & painful abdomen. Stomach can twist on own axis. Urgent veterinary treatment to avoid fatality | Familial, probably not simplex but mode of inheritance not known |
| Haemophilia A | Blood clotting disorder. Low or undetectable Factor VIII coagulant activity | Inherited - presumed X-linked recessive |
| Haemophilia B | Undetectable Factor IX (Christmas factor) coagulant activity & protein | Inherited - X-linked recessive |
| Heart Disease - Dilated Cardiomyopathy | Congested heart failure, hypertrophy & degenerated changes to heart | Familial, believe inherited, mode of inheritance unknown. Can be controlled with drugs (Vetmedin) |
| Hip Dysplasia | Faulty fitting of femoral head & acetabulum (hip joints) | Inherited - Trauma - Over exercising puppies & rough play. Limit exercise, keep weight down. Surgery |
| Portosystemic Shunt | An abnormality of the blood circulating system where blood bypasses the liver | Aetiology under investigation. Surgery |
| Thyroid Disease (Autoimmune) | Thyroid gland unable to produce sufficient hormones to sustain health. Can result in hypothyroidism | Familial. Correct thyroid imbalance - with Soloxine |
| Water babies (Anasarca) | Also known as monster pups because of their size. Normally seen in Bulldogs but I have seen one case in St Bernards | Not thought to be inherited |